Comparison of Standard Lipid Profile
vs

The VAP Advanced Cholesterol Test

Standard Lipid Profile
*Measures total cholesterol
*Measures HDL
*Calculates LDL using the Friedewald formula (LDL = TC – HDL – TRIG/5)

*Measures triglycerides
*
Requires fasting
 The  VAP Cholesterol Test
*Directly measures total cholesterol
*Directly measures HDL and separates into HDL2 and HDL3  (HDL2 is the “best” cholesterol and when low, is a risk factor for CAD, HDL3 is the least protective HDL)
*Directly measures LDL and separates into 3 components:  LDL-R;  Lp(a);  and IDL (Total LDL may be normal, but one of the 3 coponents of LDL may be elevated and indicate a risk for CAD.  Lp(a) is a genetic risk factor that, when elevated, could indicate a higher risk for heart disease.  IDL is also a genetic risk factor.)
*Measures LDL pattern density.  (Pattern A indicates large, buoyant LDL particles.  Pattern B indicates small, dense
LDL particles and is most atherogenic).
*Directly measures triglycerides.
*Directly measures triglyceride-rich lipids:  VLDL (1,2,3 and total)  (VLDL 3 is small, dense and most dangerous).
*Fasting not required.  ATPIII requires expanded lipid test when triglycerides > 400mg/dL and suggests direct measured LDL in non-fasting state.