Comprehensive Digestive Stool Analysis 2.0™ (CDSA/P 2.0) with Parasitology-Genova Kit

Note: This is a home collection test kit that will be mailed to you.

Fasting Required: No

Specimen: Stool

Lab: Genova Diagnostics

Results: 14-21 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Special Instructions: Ship to lab Monday–Friday only.
The following are interfering substances and should be discontinued unless directed otherwise by your physician: bentonite clay, betaine HCL or digestive enzymes, castor oil, mineral oil, rectal suspositorites. If you are taking a medication that isn’t listed as an interfering substance, ask your healthcare professional before stopping any prescribed substance.
2 weeks before test: If taking antibiotics or antifungals – or taking beneficial flora supplements (acidophilus, etc.) or consuming food products containing beneficial flora(e.g. Activia®) – it is recommended that you wait at least 14 days after your last dose before beginning the test (unless instructed otherwise by your physician). There may be times when you healthcare provider prefers that you stay on one of these agents (e.g. acidophilus) in order to evaluate its effectiveness. Follow your healthcare provider’s recommendation.
Eat your usual diet during the 2-3 days prior to stool collection, ideally including some fatty foods (e.g. butter or salad oils) and protein-rich foods, so that we may assess how your body processes them. Contact your healthcare provider with any questions.
2 days before the test: It is recommended that you discontinue use of over-the-counter suppressants of inflammation like aspirin and/or non-steroidal anti-inflammatory drugs(ibuprofen, Advil®, Motrin®, Nuprin®) unless requested to continue by your physician.

Description: The Comprehensive Digestive Stool Analysis 2.0™ (CDSA 2.0) is an advanced stool test that provides immediate, actionable clinical information for the management of gastrointestinal health. Utilizing cutting-edge technologies and biomarkers, this test offers valuable insight into digestive function, intestinal inflammation, and the intestinal microbiome.

The biomarkers from the CDSA 2.0 Profile are reported using the DIG framework, providing key clinical information for three main gastrointestinal functional areas:

Digestion/Absorption:Pancreatic Elastase-1 is a marker of exocrine pancreatic function. Putrefactive Short–Chain Fatty Acids (SCFAs) are markers of undigested protein reaching the colon.

Inflammation/Immunology: Calprotectin is a marker of neutrophil-driven inflammation. Produced in abundance at sites of inflammation, this biomarker has been proven clinically useful in differentiating between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). Eosinophil Protein X is a marker of eosinophil-driven inflammation and allergic response.

Gut Microbiome: Metabolic indicators demonstrate specific and vital metabolic functions performed by the microbiota. These include:
Beneficial Short–Chain Fatty Acids (SCFA), including n–Butyrate, are fermentation products produced by bacterial action on fiber and resistant starch. N-butyrate is the primary fuel source for colonocytes. pH is influenced by macronutrient composition, bacterial populations, and transit time. Beta-glucuronidase is an enzyme produced by bacteria that relates to the metabolism and detoxification of certain substances. Bacteria and mycology cultures demonstrate the presence of specific beneficial and pathogenic organisms. Bacteria and mycology sensitivities are provided for pathogenic or potentially pathogenic organisms that have been cultured. The report includes effective prescriptive and natural agents. Parasitology CDSA 2.0 provides microscopic fecal specimen examination for ova and parasites (O&P), the gold standard of diagnosis for many parasites. The report includes effective prescriptive and natural agents, MIC Sensitivities, Yeast or Bacteria and Short Chain Fatty Acids Distribution.

CDSA 2.0 is also available without parasitology.

Analytes Reported:
Bacteriology Culture, aerobic
Bacteriology Culture, aerobic x 3
Bacteriology Culture, anaerobic
Beneficial SCFAs
Bile Acids
Deoxycholic Acid
Entamoeba histolytica
Eosinophil Protein X (EPX)
LithoCholic Acid
Pancreatic Elastase
Parasite Identification, Concentrate Prep
Parasite Identification, Trichrome Stain
Putrefactive SCFAs
Yeast Culture
n-Butyrate %

Additional Biomarkers Available for add-on at additional cost:
Clostridium difficile
Fecal Fat
Helicobacter pylori
Macroscopic Exam for Worms
Occult blood
Zonulin Family Peptide