Estradiol/Testosterone (260)-BioHealth Kit

Note: This is a home collection test kit that will be mailed to you.

Fasting Required: No

Specimen: Saliva

Results: 10-14 Business Days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Collection Instructions: Place the ice gel pack flat in your freezer and freeze for at least 36 hours. On day of collections do not drink caffeine, alcohol or smoke, unless otherwise instructed by your clinician. For one hour before collection, do not brush your teeth, floss or use mouthwash. Do not eat or drink anything except water. Unless instructed otherwise avoid taking any hormones on the day of collection. Collect saliva before taking any medications or supplements.

If using any form of hormone replacement therapy, use should be suspended as follows until saliva collection is complete:
• Transdermal Creams - If using topical hormones, it is recommended that they are stopped 48-72 hours prior to saliva collection to avoid contamination of the sample or falsely elevated readings.
• Sublingual Hormones - If using sublingual hormones, it is recommended that the hormones be stopped 48-72 hours prior to saliva collection to avoid contamination of the sample or falsely elevated readings.
• Oral Micronized Progesterone and Other Oral Products - If taking oral hormones, allow 24 hours to pass from the last dosage before doing saliva collections.
• Subcutaneous Pellets – The best collections are taken midway through the life of the hormone product to avoid measurements of transient spikes in hormones when pellets
are new.
• Injectable Hormones – This primarily applies to injectable testosterone in men. Salivary samples should be taken 10-14 days after the injection giving an opportunity for the hormone
to level out.

Each test kit contains a single tube for a saliva collection. The collection should take place in the morning within an hour of waking. Specific instructions are provided in each test kit and should be read thoroughly before collecting and shipping samples.
• Premenopausal - Salivary samples for this test should be collected on days 19, 20 or 21 of a normal menstrual cycle.
• Perimenopausal - For a perimenopausal woman still cycling, the salivary samples should be taken on days 19, 20 or 21 of her cycle. If her cycles are becoming consistently shorter, the
samples should be collected 5-7 days prior to menses. If the cycles are unpredictable but still frequent, collect salivary samples on day 19, 20 or 21 of the cycle.
• Postmenopausal - For women who are in menopause, collect salivary samples on any day.
• Men – Collect sample at any time. See recommendations in kit for men who are supplementing with testosterone

Analytes Reported: Estradiol and Testosterone

Description: Estradiol is the primary estrogen, produced in the ovaries and released by the egg follicles to trigger the rest of the reproductive cycle. It is an important modulator of hormone activity in both men and women, with numerous clinical applications, including fertility, obesity, sleep disorders, and sexual dysfunction.

In men, testosterone affects sexual features and development. It is essential for normal sexual behavior, sex drive, healthy erections, and sperm production. Women rely on testosterone to maintain libido, bone density, and muscle mass throughout their lives. In both sexes, it affects many metabolic activities such as production of blood cells in bone marrow, lipid metabolism, carbohydrate metabolism, and liver function.

The combination of these two tests are important for monitoring DHEA supplementation.