Cholinesterase, Serum
Fasting Required: Yes 12 Hours

Specimen: Blood

Results: 5 - 7 Business days

Description: Approximately 1 in every 2500 individuals has inherited a defective enzyme or a deficiency of the enzyme (Pseudocholinesterase) that metabolizes succinylcholine (an anesthetic agent). With a "normal" dosage, these individuals have prolonged apnea. Such individuals are responsive at much smaller concentrations of this anesthetic agent than the general population. Low concentrations of Pseudocholinesterase are observed in individuals exposed to organophosphorous insecticides and in patients with hepatic dysfunction.

Limitations: Results may be depressed in patients who consume oral contraceptives. Hepatic disease may cause up to a 70% decrease in enzyme levels. Cholinesterase may be slightly elevated in patients with obesity or diabetes.

Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.