Menopause Plus™ with CAR and Adrenocortex Stress-Genova Kit

Note: This is a home collection test kit that will be mailed to you.



Fasting Required: Yes - See Special Instructions

Specimen: 8 saliva samples collected over a 6-day period (frozen)

Special Instructions: Transdermal (cream) and sublingual bio-identical hormones may produce artificially high levels in the saliva that do not correlate with blood levels. This increase from cream hormones may last for weeks to months after discontinuing use. If you are taking these substances – or have taken them within the last 12 months – please consult with your healthcare practitioner before taking this test.

The following drugs and herbs may influence levels of hormones reported in this test: ketoconazole, clomiphene, phenytoin, oral steroids (e.g. Prednisone), cortisone cream or patches, and any steroid-based nasal sprays, inhalers, or eye drops; DHEA sublingual pellets or drops. Let your physician know about these and any other medications, herbs, and supplements that you have used in the past 3 months. Do not change use of supplements or medications unless instructed to do so by your healthcare provider.
It is important that you collect saliva during the specified time frame. One hour prior to collection do not eat, brush or floss your teeth, use mouthwash, chew gum or use any tobacco products. You may drink ONLY water during this time.

Results: 7-10 business days

Description: Eight specimens – collected over six days – are examined for levels of estradiol, estrone, estriol, progesterone, the progesterone/estradiol ratio (P/E2), and testosterone. In addition to thorough evaluation of the sex hormones, Menopause Plus also evaluates DHEA, cortisol, and melatonin for the broadest scope of clinical insight.

To enhance clinical utility, in addition to evaluating patient results against various healthy cohort reference ranges, a therapeutic cohort results cover page is provided for the clinician to quickly and conveniently observe where patient results fall in comparison to a cohort of peri/menopausal women treated with bioidentical hormone therapy.

The Menopause Plus hormone test provides information about the impact that shifting hormone levels can have in women during perimenopause and menopause and in men during andropause (male menopause). In addition, imbalances of other steroid hormones, such as DHEA, cortisol, and melatonin, can influence sex-hormone production.

Cortisol Awakening Response (CAR): is a transient, immediate rise in cortisol upon awakening and is distinct from the diurnal rhythm. CAR reflects a person's ability to cope with anticipated challenges and their perception of control around chronic stress, providing insight into HPA axis resiliency.

The isolated evening cortisol has distinct clinical implications. Elevated evening cortisol is linked to insomnia and associated with various diseases such as diabetes, cardiovascular disease, hormonally driven cancers, and osteoporosis.

Adrenocortex Stress Profile (ASP): Four salivary samples measured throughout the day to give insight into the natural circadian diurnal cortisol rhythm, and help clinicians address specific daily stressors.

Analytes Reported:
Cortisol
DHEA
Estradiol
Estriol
Estrone
Melatonin
Progesterone
Testosterone

Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.