IGF Binding Protein-3 (IGFBP-3)
Fasting Required: No

Specimen: Blood

Lab: Quest Diagnostics

Results: 3-5 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Description: The main reason doctors order the IGFBP-3 test is for its usefulness as an indicator of whether someone is producing a normal amount of human growth hormone. In this way, the IGFBP-3 test is used to check for pituitary gland disorders and abnormalities in growth hormone production.

Advantages of IGFBP-3 over IGF-1 are the higher levels in young children which gives a better insight between normal and subnormal levels. The IGFBP-3 assay is also used to diagnose children with short stature having normal GH levels. Some children with short stature give subnormal IGF-I levels despite normal GH levels. IGFBP-3 was found to be a more reliable parameter for monitoring the usefulness of therapy. Therefore, it is a useful aide to the measurement of IGF-I.

Alternate Name(s): Insulin-Like Growth Factor Binding Protein