DUTCH Cycle Mapping + DUTCH Complete-Precision Analytical Inc. Kit

Note: This is a home collection test kit that will be mailed to you.

Fasting Required: No

Specimen: 25 dried urine samples taken directly upon waking

Lab: Precision Analytical

Results: 10-14 business days

Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Food Restrictions: Avoid the following foods within 48 hours of testing; avocado, bananas and fava beans. If you happen to consume some of these foods, please make a note of it on your requisitions form.

Supplement Restrictions: Some supplements/medications may impact organic acid results. If you take any of the following, please consult your provider: 5-HTP, Tryptophan, SAMe, Tyrosine, L-Dopa, DL-Phenylalanine (DLPA), Macuna, Quercetin and St. John's Wort.

Patient Instructions: It is typically required to discontinue any estrogen or progesterone therapy for this test.
You will be collecting a series of samples throughout the course of one menstrual cycle. Cycling: Day 1 of your cycle should be considered the first day with menstrual flow (not just spotting). Collection will begin on the seventh day of your cycle. The last 4 samples will be collected on the fourth day after your next cycle start date.Non-Cycling: (Functional ovaries without regular menstrual bleeding) Start collections any day.

Results:For some women, testing reproductive hormones (progesterone, estrogen, etc.) on a single day is sufficient. In other scenarios, the clinical picture cannot be properly captured without “mapping” out the hormonal pattern throughout their menstrual cycle. The expected pattern of hormones shows relatively low estrogen levels early in the cycle, a surge around ovulation and modest levels in the latter third of the cycle (the luteal phase). Progesterone levels, on the other hand, stay relatively low until after ovulation. After ovulation levels ideally increase (>10-fold) and then drop back down at the end of the cycle. A disruption in this cycle can lead to infertility or hormonal imbalance.

The DUTCH Complete test is the most comprehensive analysis of sex and adrenal hormones. This profile includes the DUTCH Adrenal and Sex Hormone Metabolite as well as an overnight melatonin measurement.

Analytes Tested:
Free cortisol (4)
Free cortisone (4)
creatinine (4)
Progesterone metabolites (a-pregnanediol, b-pregnanediol)
androgen metabolites (DHEAS, etiocholanolone, androsterone, testosterone, 5a-DHT, 5a-androstanediol, 5b-androstanediol, epi-testosterone) estrogen metabolites (estrone, estradiol, estriol, 2-OH-estrone, 4-OH-estrone, 16-OH-estrone, 2-Methoxy-estrone, 2-OH-estradiol)